Creative Biolabs is an undisputed world-leading service provider and research institution in phage display library technique. We offer following world-class premade human and mouse antibody libraries with great capacity & diversity that can derive highly specific, high affinity antibodies ranging from 10 pM to 10 nM.
During the past decades, we have integrated a comprehensive portfolio of premade antibody libraries, including human scFv libraries, human Fab libraries, mouse scFv/Fab libraries, rabbit Fab libraries, chicken scFv libraries and single domain antibody libraries. We also offer multiple high-quality premade antibody libraries for yeast display.
HuScL-2: Human Single Chain Antibody Library
Phagemid phage display system
M13 pIII fusion containing short 6xHis and c-Myc detection tag
VH-VL format scFv library
Human antibody genes from semi-synthesis
Capacity: 1.42×109
Proliferation in TG1 cells
Production of soluble antibody fragments in HB2151
Helper phage KM13
HuScL-3: Human Single Chain Antibody Library
Phagemid phage display system
M13 pIII fusion containing short 6xHis and V5 detection tags
VH-VL format scFv library
Collections of human antibody genes from non-immunized donors
VL/VH chain recombination through an integrated Cre/lox system
Capacity: 1.6×109
Proliferation in TG1 cells
Production of soluble antibody fragments in HB2151
Helper phage M13KO7
These libraries have a size ranging from 106 to 1011 and cover most commonly used antibody formats, including scFv, Fab, scFab, full-length IgG and Fn3. Comprehensive library types and various genetic backgrounds give these libraries multiple functions and applications. In combination with the Ultraff™ Yeast Display Technology or Yeast Mating Technology from Creative Biolabs, low nanomolar, even picomolar-affinity antibodies of different formats are routinely obtained. All human antibody libraries for yeast display licensed from Creative Biolabs can be amplified 1010 fold under proper operation, without measurable loss of clonal diversity, allowing effectively indefinite expansion. Creative Biolabs’ top quality human antibody libraries for yeast display can improve your results and save your time in novel antibody discovery.
Figure 1. Four types of antibody libraries(Ref: High Affinity, Developability and Functional Size: The Holy Grail of Combinatorial Antibody Library
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